FOR SPONSORS AND CROS
Clinical Trial Site Partner for Sponsors and CROs
Sequoia Clinical Research is a connected clinical trial site network helping sponsors and CROs accelerate study start-up, enrollment, and execution through shared operations, experienced investigators, and established patient access.
Why Sponsors and CROs Choose Sequoia
Accelerated Study Start-Up
Shared regulatory, administrative, and operational processes simplify study activation, from contracts and IRB submissions through site preparation.
50+ First-in-Human trials supportede a50+ First-in-Human trials supportedpreparation.
Enhanced Patient Recruitment
Established patient relationships, centralized recruitment, and experienced clinical teams support efficient screening, enrollment, and retention across Sequoia's network.
500+ completed trials
Multiple Sites. One Contact. One Agreement.
One agreement and a centralized point of contact simplify contracting, legal, and financial coordination across multiple Sequoia sites.
1 AGREEMENT
Access across multiple Sequoia sites
Site Selection Support
Clinical Trial Site Selection:
How Sequoia Qualifies as Your Partner
During clinical trial site selection, sponsors determine whether a research site has the appropriate population access, infrastructure, investigator expertise, and enrollment history to successfully execute a study. Sponsors typically evaluate potential partners across four key criteria.
Patient Population Access
Patient population access begins with established community relationships, not recruitment campaigns.
During clinical trial site selection, sponsors evaluate a site’s recruitment capabilities across the required populations through patient databases, EHR insights, referral relationships, and prior enrollment performance. Sequoia has established patient relationships in Kansas City and Houston across vaccine, nephrology, GLP-1, metabolic, and cardiovascular research areas.
Site Infrastructure & Regulatory Readiness
Purpose-built research infrastructure supports consistent execution from activation through closeout.
Dedicated research facilities, experienced clinical operations teams, pharmacy capabilities, and a strong regulatory track record support complex study protocols.
Principal Investigator Qualifications
Experienced investigators provide therapeutic expertise and clinical leadership across the network.
Sequoia's investigator network spans vaccines, metabolic disease, cardiovascular research, nephrology, and Phase I studies, supported by centralized clinical and medical oversight.
Enrollment Track Record
Proven enrollment performance helps reduce execution risk before a study begins.
Sequoia brings experience across hundreds of completed trials, supported by established patient populations and a history of meeting enrollment commitments.
Site Activation Support
How Sequoia Accelerates Clinical Trial Site Activation
Clinical trial site activation involves preparing and authorizing a research site for participant enrollment by securing regulatory approvals, determining operational readiness, and finalizing sponsor verification before screening the first participant.
5-Component Workflow:
01
Regulatory and Ethics Readiness:
Coordinate IRB approval, informed consent documentation, investigator qualifications, and regulatory submissions.
02
Contract and Budget Negotiations:
Centralized coordination of contracts, budgets, legal review, and financial documentation.
03
Investigator Site File Compliance:
Maintain essential regulatory documentation and inspection-ready study files.
04
Operational Setup and Training
Complete protocol training, GCP requirements, EDC setup, and eConsent configuration.
05
Site Initiation Visit:
Confirm regulatory, operational, and protocol readiness before First Patient In.
Site Activation Checklist:
- Clinical Trial Agreement (CTA) executed
- IRB / Ethics Committee approval received
- FDA Form 1572 submitted
- Site staff GCP-trained
- EDC / eConsent system access granted
- Investigational product received and accounted for
- SIV scheduled and confirmed
- Site activation confirmed
Trusted by Leading Sponsors and CROs
500+
Completed
Trials
200+
Vaccine
Trials
23
FDA-Approved Drugs & Vaccines
Funded by BARDA, NIH & Department of Defense
50+
Phase 1 /
First-in-Human Trials
Deep Therapeutic Expertise
Across Key Indications
Sequoia’s therapeutic expertise is grounded in investigator experience, documented study history, and access to relevant patient populations. Explore the therapeutic areas where Sequoia brings the greatest depth of clinical and operational experience.
GLP-1 / Obesity / Metabolic
Dr. Damaris Vega, Dr. Mona Mounla & Dr. Harbison
Established patient access, diverse populations, and targeted recruitment strategies support metabolic research.
Cardiovascular / Cardiometabolic
Dr. Heath Wilt
Experienced investigators and established patient populations support studies across key cardiovascular indications.
Nephrology
Dr. Ahmed Awad
Experienced nephrology investigators supported by a track record of up to 50 completed trials.
Vaccines
Dr. Carlos Fierro
Extensive vaccine experience supported by rapid start-up, strong enrollment, and specialized research capabilities.
FAQs for Sponsors and CROs
What is a clinical trial site partner?
A clinical trial site partner is a specialized research organization that collaborates with pharmaceutical companies and CROs to execute clinical trials by recruiting eligible participants, running the study protocol, and maintaining regulatory compliance and consistent data quality. Sequoia Clinical Research performs this role across multiple connected facilities in the greater Kansas City and Houston metros, all under one shared quality system.
What does a clinical trial site partner do for sponsors and CROs?
A clinical trial site partner handles the day-to-day site execution required by sponsors and CROs by assessing protocol feasibility, recruiting and screening eligible participants, collecting data, and maintaining regulatory compliance throughout a study. Sequoia provides direct, ongoing progress reports to sponsor and CRO teams so they have visibility into site performance at every stage of research.
How is a clinical trial site network different from a CRO?
A CRO often manages broader trial operations on behalf of a sponsor, whereas a clinical trial site network like Sequoia provides principal investigators (PIs), research facilities, patient access, and site-level execution where the study is conducted. Many trials use both: a CRO to manage the program and a site network to conduct enrollment and collect data.
What criteria do sponsors use to evaluate a clinical trial site?
Sponsors typically evaluate patient population access, site infrastructure and regulatory readiness, Principal Investigator qualifications, and an enrollment track record. Sequoia addresses these criteria through established patient relationships in Kansas City and Houston, a dedicated research facility with an in-house pharmacy team, named PIs with decades of combined experience, and 500+ completed trials.
What does clinical trial site selection involve?
Clinical trial site selection generally includes feasibility assessment, protocol review, PI qualification review, site infrastructure review, regulatory submission review, and contracting. Sequoia supports these steps through centralized administrative, regulatory, and operational coordination across its Kansas City and Houston locations, giving sponsors a single point of contact throughout site qualification.
What is clinical trial site activation and what does it include?
Clinical trial site activation prepares and authorizes a research site to enroll patients. It includes regulatory and ethics readiness, contract and budget finalization, investigator site file compliance, operational setup and staff training, and the Site Initiation Visit that confirms inspection readiness before the first patient is enrolled
What sponsors and CROs has Sequoia worked with?
Sequoia has supported studies across vaccine, metabolic, and nephrology research for sponsors including GSK, Pfizer, Moderna, Sanofi, AstraZeneca, BioNTech, Novavax, Janssen, and Roche, and has worked alongside CROs including IQVIA, PPD/Labcorp, Syneos Health, ICON, and Parexel. Sequoia's research has also been funded in part by BARDA, NIH, and the Department of Defense.
How do I start a conversation about partnering with Sequoia for a clinical trial?
Request a feasibility conversation → [LINK: /contact] through Sequoia’s sponsor contact form. The team will review the protocol for fit across the Kansas City and Houston sites, then schedule a site qualification conversation with the appropriate principal investigator.